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Cholula is a city in the Mexican state of Puebla. The official, though little used, full name of the city is Cholula de Rivadavia. The city of Cholula is divided into two municipalities, San Andrés Cholula and San Pedro Cholula, which are considered to be part of the conurbation of the city of Puebla, and a third, more rural municipality called Santa Isabel Cholula.
Cholula, or in Nahuatl Cholōllān, was an important city of pre-Columbian Mesoamerica, dating back to at least the 2nd century BC, with settlement as a village going back at least some thousand years earlier.
Cholula was a major center contemporary with Teotihuacan and seems to have avoided, at least partially, that city's fate of violent destruction at the end of the Mesoamerican Classic period. Cholula thus remained a regional center of importance, enough so that, at the time of the fall of the Aztec empire, Aztec princes were still formally anointed by a Cholulan priest in a manner reminiscent, and perhaps even analogous, to the way some Mayan princes appear to have come to Teotihuacan in search of some sort of formalization of their rulership.
At the time of the arrival of Hernán Cortés Cholula was second only to the Aztec capital Tenochtitlan (modern Mexico City) as the largest city in central Mexico, possibly with a population of up to 100,000 people. In addition to the great temple of Quetzalcoatl and various palaces, the city had 365 temples.
During the Spanish Colonial period, however, Cholula was overtaken in importance by the nearby city of Puebla.
Cholula is most famous as the site of the Great Pyramid of Cholula, the largest man-made pyramid and monument by volume in the world.

http://en.wikipedia.org/wiki/Cholula,_Puebla